ABSTRACT
Latent tuberculosis was studied in a research laboratory. A prevalence of positive tuberculin skin test results (> 15mm) of 20 percent was found and the main predictors were place of birth in a foreign country with high prevalence of tuberculosis and a history of contact with patients with untreated active tuberculosis.
A tuberculose latente foi estudada em um laboratório de investigação. Foi encontrada uma prevalência de 20 por cento de resultados positivos para o teste cutâneo de tuberculina (> 15mm) e os principais fatores preditores foram ser natural de um país estrangeiro com alta prevalência de tuberculose e ter uma história de contato com doentes com tuberculose ativa não tratada.
Subject(s)
Adult , Female , Humans , Male , Middle Aged , Young Adult , Laboratory Personnel/statistics & numerical data , Mycobacterium tuberculosis/isolation & purification , Tuberculosis, Pulmonary/epidemiology , Foreign Professional Personnel , Infectious Disease Transmission, Patient-to-Professional , Prevalence , Risk Factors , Tuberculin Test , Tuberculosis, Pulmonary/diagnosis , Tuberculosis, Pulmonary/transmission , Young AdultABSTRACT
Immunity to intracellular bacteria including Mycobacterium tuberculosis. Mycobacterium leprae, and Listeria monocytogenes depends on specific T cells. Evidence to be described suggests that CD4 (alpha/beta)T cells which interact with each other and with macrophages contribute to acquired resistence against as well as pathogenesis of intracellular bacterial infections